(3,4-dichlorophenyl)hydrazine monohydrochloride

(3,4-dichlorophenyl)hydrazine monohydrochloride - Names and Identifiers

Name	3,4-Dichlorophenylhydrazine hydrochloride
Synonyms	3,4-DICHLOROPHENYLHYDRAZINE HCL (3,4-dichlorophenyl)diazanium chloride 3,4-DICHLOROPHENYLHYDRAZINE HYDROCHLORIDE 3,4-Dichlorophenylhydrazine hydrochloride 3,4-Dichoropheynylhydrazine hydrochloride 1-(3,4-DICHLOROPHENYL)HYDRAZINE HYDROCHLORIDE (3,4-dichlorophenyl)hydrazine monohydrochloride
CAS	19763-90-7
EINECS	243-278-0
InChI	InChI=1/C6H6Cl2N2.ClH/c7-5-2-1-4(10-9)3-6(5)8;/h1-3,10H,9H2;1H

(3,4-dichlorophenyl)hydrazine monohydrochloride - Physico-chemical Properties

Molecular Formula	C6H7Cl3N2
Molar Mass	213.49
Melting Point	230°C (dec.)(lit.)
Boling Point	288.3°C at 760 mmHg
Flash Point	128.2°C
Vapor Presure	0.00236mmHg at 25°C
Appearance	White powder
BRN	3703934
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
MDL	MFCD00012937

(3,4-dichlorophenyl)hydrazine monohydrochloride - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
UN IDs	2811
WGK Germany	3
HS Code	29280000
Hazard Note	Harmful/Irritant
Hazard Class	IRRITANT

(3,4-dichlorophenyl)hydrazine monohydrochloride - Reference Information

application

3, 4-dichlorophenylhydrazine hydrochloride is a pharmaceutical intermediate that can be used to prepare biphenylpyridine.

preparation method

compound 3,4-dichloroaniline (38.88g,0.2399mol) is dissolved in dichloroethane (30ml), then 12mol/L concentrated hydrochloric acid (70ml,0.84mol) is added, sodium nitrite (18.06g,0.261mol) is added, the reaction solution is stirred at 5 ℃ for 30min, and the clarified liquid is filtered out, drop to 140ml of sodium sulfite solution containing (90.71g,0.7197mol), react at 80 ℃ for about 3 hours, react to produce 3,4-dichlorophenylhydrazine, add about (60ml,0.72mol) concentrated hydrochloric acid for 1 hour, stir overnight at room temperature, filter to obtain 3,4-dichlorophenylhydrazine hydrochloride white solid 46.1g, yield: 90%.

Last Update：2024-04-10 22:29:15